蒋光彬，男，汉族，广西桂林人，理学博士。现于金沙3777从事教学与科研工作。
一、教学与工作经历
1. 2018.07—至今 金沙3777，金沙3777，化学与化工教研室任教，2018年晋升讲师，2021年晋升副教授。
2. 2020.07—2020.12月 桂林三棱生物科技有限公司，专项调研与方案策划；
3. 2015.09—2018.06 华南理工大学，化学与化工学院，有机化学专业，博士；
4. 2012.09—2015.06 广东药科大学，药学院，药物化学专业，硕士；
5. 2008.09—2012.06 齐齐哈尔医学院，药学院，药学专业，学士；
二、教学工作
本科教学专业：化学工程与工艺，应用化学，能源化工，给水排水工程，高分子材料与工程；本科教学课程：《有机化学》、《工业药剂学》、《化学工程与工艺专业实验》、《有机化学实验》《制药工程综合实训》等；指导化学工程与工艺专业本科毕业设计（论文）、生产实习等。2019年开始硕士研究生招生，截止2021年10月，指导硕士研究生6名。
三、研究工作
主要研究方向：
1、绿色有机合成方法学研究：利用过渡金属催化、光催化、电氧化等策略构建不易制备的功能分子，实现药物活性分子的结构修饰。
2、新型抗菌、抗肿瘤药物分子的合成及生物活性机制研究：制备新型钌金属配合物、小分子氮杂环化合物等，筛选它们的抗菌(Staphylococcus Aureus)、抗肿瘤（A549、HepG-2、Hela、MCF-7等）活性，同时研究构效关系，促进先导化合物的发现，同时对活性优良化合物的生物活性机制进行深入研究。
主持或参与的科研项目：
1. 2022.01—2025.12 国家自然科学基金项目—地区基金（项目编号：22167011） 主持在研，35万；
2. 2019.03—2022.02 广西自然科学基金-青年基金(项目编号：2018GXNSFBA050024) 主持在研，10万；
3. 2020.12—2023.12 广西自然科学基金-面上项目（项目编号：2020GXNSFAA297227） 主持在研，10万；
4. 2020.01—2022.12 广西科技基地和人才专项（项目编号：桂科AD19245008） 主持在研，10万；
5. 2021.06—2022.12重点实验室开放基金-主任基金（项目编号：EMFM20211123）主持在研，5万；
6. 2018.09—2021.12 金沙3777科研启动经费（项目编号：GLUTQD2018056） 主持在研，10万；
7. 2019.06—2022.05广西科技基地和人才专项（项目编号：桂科AD19110110） 参与在研，12万。
8. 2019.01-2022.12 国家自然科学基金-面上项目（项目编号：21871098） 参与在研，64万；
9. 2018.01-2020.12 国家自然科学基金-青年基金（项目编号：21702064） 参与结题，25万；
10. 2017.01-2020.12 国家自然科学基金-面上项目（项目编号：21871098） 参与结题，65万。
四、近期主要论著
目前已在Org. Lett.; Chem. Commun.; Org. Chem. Front. Adv. Synth. Catal.; J. Org. Chem.; Appl. Organomet. Chem.; Org. Biomol. Chem.; Eur. J. Med. Chem.; J. Inorg. Biochem.; Spectrochim. Acta. A Mol. Biomol. Spectrosc.; New. J. Chem.; J Photoch. Photobio. B; PloS one.等国内外学术期刊上发表SCI收录论文30余篇，引用频次超700；H-因子 = 20。此外，申请发明专利十余项，受邀担任J. Org. Chem.、 Dalton. Trans.、 Inorg. Chem.、 J. Biol. Inorg. Chem.、 RSC Adv. 等重要国际SCI期刊的审稿专家。代表性成果如下：
2023年
34. Hongsheng Nie, Zhicheng Xiong, Meiqian Hu, Shuai Zhang, Changsheng Qin, Shoucai Wang, Fanghua Ji*, Guangbin Jiang*, Copper-Catalyzed Sulfonylation Reaction of NH-Sulfoximines with Aryldiazonium Tetrafluoroborates and Sulfur Dioxide: Formation of N-Sulfonyl Sulfoximines; J. Org. Chem., 2023, 88, 2322–2333.
2022年：
33. Guang Yang, Zhicheng Xiong, Hongsheng Nie, Meiqin He, Qiong Feng, Xuan Li, Huabin Huang, Shoucai Wang, Fanghua Ji*, Guangbin Jiang*, Copper-Catalyzed Divergent C-H Functionalization Reaction of Quinoxalin-2(1H)-ones and Alkynes Controlled by N1-substituents for the Synthesis of (Z)-enaminones and Furo[2,3-b]quinoxalines; Org. Lett., 2022, 24, 1859−1864.
32. Chen Kang, Jiawei Xu, Xuan Li, Shoucai Wang, Guangbin Jiang*, Fanghua Ji*, Oxidative C−H/N−H Carbonylation of Benzamide by Nickel Catalysis with CO as the Carbonyl Source; J. Org. Chem., 2022, 87, 10390-10397.
31. Guang Yang, Shoucai Wang, Hongsheng Nie, Zhicheng Xiong, Xuan Li, Fanghu Ji,* Guangbin Jiang.* An efficient transition metal-free difunctionalization of alkenes in water for the green preparation of sulfone compounds; Appl. Organomet. Chem., 2021, e6470. https://doi.org/10.1002/aoc.6470.
2021年：
30. Guangbin Jiang,* Guang Yang, Xinqiang Liu, Shoucai Wang, and Fanghua Ji.* Palladium-Catalyzed Sequential Acylation/Annulation of Indoles with Acyl Chlorides Using Primary Amine as the Directing Group; New J. Chem., 2021, 45， 104-109.
29. Guang-Bin Jiang,* Wen-Yao Zhang, Miao He, Yi-Ying Gu, Bai Lan, Yang-Jie Wang, Qiao-Yan Yi, Fan Du. Systematic evaluation of the antitumor activity of three ruthenium polypyridyl complexes; J. Inorg. Biochem., 2021, 225, 111616.
28. Xiangwen Liao, Jiang Wang, Guijuan Jiang, Lingyu Mao, Guangbin Jiang, Jintao Wang, Bin Huang. Identification of ruthenium (II) complexes with furan-substituted ligands as possible antibacterial agents against Staphylococcus aureus; Chem. Biol. Drug. Des., 2021, 98, 885-893.
27. Xiangwen Liao, Lianghong Liu, Yanhui Tan, Guijuan Jiang, Haihong Fang, Yanshi Xiong, Xuemin Duan, Guangbin Jiang and Jintao Wang. Synthesis of ruthenium complexes functionalized with benzothiophene and their antibacterial activity against Staphylococcus aureus, Dalton Trans., 2021, 50, 5607–5616.
26. Xiangwen Liao, Bin Huang, Guangbin Jiang, Guijuan Jiang, Xiaoli Lin, Yanshi Xiong, Xuemin Duan, Jintao Wang. Investigation of Antibacterial Activity Against Staphylococcus Aureus Of Ruthenium(II) Complexes Containing Furan-Substituted Ligands; http://dx.doi.org/10.2139/ssrn.3782143.
2020年：
25. Showcai Wang, Siyu Zhang, Meichen Liu, Jiawang Zang, Guangbin Jiang* and Fanghua Ji.* Palladium-catalyzed C3-selective C–H oxidative carbonylation of imidazo[1,2-a]pyridines with CO and alcohols: a way to access esters; Org. Chem. Front. 2020, 7, 697-701.
24. Shoucai Wang, Xuan Li, Jiawang Zang, Meichen Liu, Siyu Zhang, Guangbin Jiang* and Fanghua Ji.* Palladium-Catalyzed Multistep Tandem Carbonylation/N-Dealkylation/Carbonylation Reaction: Access to Isatoic Anhydrides; J. Org. Chem. 2020, 85, 2672-2679.
23. Guang-Bin Jiang,* Wen-Yao Zhang, Miao He, Yi-Ying Gu, Lan Bai, Yang-Jie, Wang, Qiao-Yan Yi, Fan Du. New ruthenium polypyridyl complexes functionalized with fluorine atom or furan: Synthesis, DNA-binding, cytotoxicity and antitumor mechanism studies; Spectrochim. Acta. A Mol. Biomol. Spectrosc., 2020, 227, 117534.
22. Guang-Bin Jiang,* Wen-Yao Zhang, Miao He, Yi-Ying Gu, Lan Bai, Yang-Jie, Wang, Qiao-Yan Yi, Fan Du. Development of four ruthenium polypyridyl complexes as antitumor agents: Design, biological evaluation and mechanism investigation; J. Inorg. Biochem., 2020 208, 111104.
21. Xuan Li, Shoucai Wang, Jiawang Zang, Meichen Liu, Guangbin Jiang* and Fanghua Ji.* Copper- and DMF-mediated switchable oxidative C–H cyanation and formylation of imidazo[1,2-a]pyridines using ammonium iodide; Org. Biomol. Chem., 2020, 18, 9100.
20. Xiangwen Liao,* Guijuan Jiang, Jintao Wang, Xuemin Duan, Zhouyuji Liao, Xiaoli Lin, Jihong Shen, Yanshi Xiong and Guangbin Jiang.* Two ruthenium polypyridyl complexes functionalized with thiophen: synthesis and antibacterial activity against Staphylococcus aureus; New J. Chem., 2020, 44, 17215.
19. Simeng Bu,‡ Guijuan Jiang,‡ Guangbin Jiang,‡ Jinyao Liu, Xiaoli Lin, Jihong Shen, Yanshi Xiong, Xuemin Duan, Jintao Wang, Xiangwen Liao, J. Biol. Inorg. Chem., 2020, 25, 747-757. (‡ = 共同一作)
2019年：
18. Guangbin Jiang,* Shoucai Wang, Jun Zhang, Jianwen Yu, Ziang Zhang, Fanghua Ji.* Palladium-Catalyzed Primary Amine-Directed Decarboxylative Annulation of α-Oxocarboxylic Acids: Access to Indolo[1,2-a] quinazolines; Adv. Synth. Catal. 2019, 361, 1798–1802.
17. Guang-Bin Jiang,* Wen-Yao Zhang, Miao He, Yi-Ying Gu, Lan Bai, Yang-Jie, Wang, Qiao-Yan Yi, Fan Du. Design and Synthesis of New Ruthenium Polypyridyl Complexes with Potent Antitumor Activity in Vitro; Spectrochim. Acta. A Mol. Biomol. Spectrosc., 2019, 220, 117132.
16. Guang-Bin Jiang,* Wen-Yao Zhang, Miao He, Yi-Ying Gu, Lan Bai, Yang-Jie, Wang, Qiao-Yan Yi, Fan Du. Anticancer Activity of Two Ruthenium(II) Polypyridyl Complexes Toward Hepatocellular Carcinoma HepG-2 cells, Polyhedron, 2019, 169, 209-218.
15. Shoucai Wang, Kai, Wang, Xiangfei Kong, Shuhua Zhang, Guangbin Jiang,* Fanghua Ji.* DMF as Methine Source: Copper-Catalyzed Direct Annulation of Hydrazides to 1,3,4‐Oxadiazoles; Adv. Synth. Catal. 2019, 361, 3986-3990.
14. Wanqing Wu,* Songjia Fang, Guangbin Jiang, Meng Li, Huanfeng Jiang.* Palladium-catalyzed regioselective C–H alkynylation of indoles with bromoalkynes in water; Org. Chem. Front. 2019, 6, 2200-2204.
13. Songjia Fang, Guangbin Jiang, Meng Li, Zhenying Liu, Huanfeng Jiang,* Wanqing Wu.* Palladium-catalyzed regioselective C–H alkynylation of indoles with haloalkynes: access to functionalized 7-alkynylindoles; Chem. Commun. 2019, 55, 13769-13772.
2018年以前：
12. Guangbin Jiang, Weigao Hu, Jianxiao Li, Chuanle Zhu, Wanqing Wu, Huanfeng Jiang.* Palladium-catalyzed primary amine-directed regioselective mono- and di-alkynylation of biaryl-2-amines. Chem. Commun., 2018, 54, 1746-1749.
11. Guangbin Jiang, Songjia Fang, Weigao Hu, Jianxiao Li, Chuanle Zhu, Wanqing Wu, Huanfeng Jiang.* Palladium-Catalyzed Sequential C(sp2)-H Alkynylation/Annulation of 2-Phenylphenols with Haloalkynes Using Phenolic Hydroxyl as the Traceless Directing Group. Adv. Synth. Catal. 2018, 360, 2297-2302.
10. Guangbin Jiang, Jianxiao Li, Chuanle Zhu, Wanqing Wu, Huanfeng Jiang.* Palladium-Catalyzed Sequential Nucleophilic Addition/Oxidative Annulation of Bromoalkynes with Benzoic Acids To Construct Functionalized Isocoumarins. Org. Lett., 2017, 19, 44440-4443.
9. Guangbin Jiang, Chuanle Zhu, Jianxiao Li, Wanqing Wu, Huanfeng Jiang.* Silver-Catalyzed Regio- and Stereoselective Thiocyanation of Haloalkynes: Access to (Z)-Vinyl Thiocyanates. Adv. Synth. Catal. 2017, 359, 1208-1212.
8. Guangbin Jiang, Junhua Yao, Ji Wang, Wei Li, Binjie Han, Yangyin Xie, GanJian Lin, Hongliang Huang, Yunjun Liu.* The induction of apoptosis in BEL-7402 cells through the ROS-mediated mitochondrial pathway by a ruthenium(II) polypyridyl complex. New. J. Chem., 2014, 38, 2554-2563.
7. Guangbin Jiang, Xiang Zheng, Junhua Yao, Binjie Han, Wei Li, Ji Wang, Hongliang Huang, Yunjun Liu.* Ruthenium(II) polypyridyl complexes induce BEL-7402 cell apoptosis by ROS-mediated mitochondrial pathway. J. Inorg. Biochem.; 2014, 141, 170-179.
6. Guangbin Jiang, Yangyin Xie, Ganjian Lin, Hongliang Huang, Zhenghua Liang, Yunjun Liu.* Synthesis, characterization, DNA interaction, antioxidant and anticancer activity studies of ruthenium(II) polypyridyl complexes. J Photoch. Photobio. B., 2013, 129, 48-56.
5. Guangbin Jiang, Wei Li, Ji Wang, Binjie Han, Ganjian Lin, Yangyin Xie, Hongliang Huang, Yunjun Liu.* Apoptosis in BEL-7402 cells induced by ruthenium(II) complexes through a ROS-mediated mitochondrial pathway. Transit. Metal. Chem., 2014, 39, 849-858.
4. Weigao Hu, Meng Li, Guangbin Jiang, Wanqing Wu, Huanfeng Jiang.* Synthesis of 2,3-Difunctionalized Benzofuran Derivatives through Palladium-Catalyzed Double Isocyanide Insertion Reaction. Org. Lett., 2018, 29, 3500-3503.
3. Chuanle Zhu, Pengquan Chen, Rui Zhu, Guangbin Jiang, Zhiming Lin, Wanqing Wu, Huanfeng Jiang.* Conversion of Triple Bonds to Single Bonds in a Domino Carbopalladation with Norbornene. Chem. Asian J., 2017, 12, 2991-2995.
2. Bingjie Han, Guangbin Jiang, Ji Wang, Wei Li, Hongliang Huang, YunJun Liu.* The studies on bioactivity in vitro of ruthenium(II) polypyridyl complexes towards human lung carcinoma A549 cells. RSC Adv., 2014, 4, 40899-40906.
1. Xiuzhen Wang, Guangbin Jiang, Ganjian Lin, Hongliang Huang, Yangyin Xie, Yunjun Liu.* Synthesis, molecular structure, DNA-binding, cytotoxicity, apoptosis and antioxidant activity of compounds containing aryloxazole. Eur. J. Med. Chem., 2014, 80, 192-200.
五、授权专利
4. 蒋光彬，王守才，及方华，一种吲哚并[1,2-a]喹喔啉衍生物的合成方法，2022.06，中国，ZL201911263114.4.
3. 及方华，王守才，蒋光彬，以DMF为甲酰化试剂构建2-(2-萘基)咪唑[1,2-a]吡啶-3-醛的新方法，2022.04，中国，ZL201910712828.2.
2. 江焕峰，蒋光彬，马志强，伍婉卿, 一种合成烯基硫氰酸酯衍生物的新方法, 2018.09.14, 中国, ZL201610579617.2.
1. 刘云军，蒋光彬，黄宏靓，李伟，韩冰洁, 一种对称性钌金属化合物及其作为制备抗肿瘤药物的应用, 2017.05.03, 中国, ZL201410621001.8.
六、联系方式
通信地址：桂林市雁山区雁山街319号，金沙3777金沙3777(541004)
E-mail：jianggb@glut.edu.cn
